FOLR4 Antibody (TH6)

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Flow Cytometry: FOLR4 Antibody (TH6) [NBP2-26651] - Analysis using the Allophycocyanin conjugate of NBP2-26657. Staining using FOLR4 antibody. CD25+ gated mouse splenocytes probed using rat IgG2b isotype control ...read more
Flow Cytometry: FOLR4 Antibody (TH6) [NBP2-26651] - Analysis of FITC conjugate of NBP2-26651. Analysis using folate receptor 4 antibody. Tri-color staining of BALB/c splenocytes for FR4 FITC (NBP2-26659 and NBP2-26660 ...read more
Flow Cytometry: FOLR4 Antibody (TH6) [NBP2-26651] - Analysis using Azide Free version of NBP2-26651. Analysis using folate receptor 4 antibody. CD4/25+ gated mouse splenocytes probed using A) rat IgG2b isotype control ...read more
Flow Cytometry: FOLR4 Antibody (TH6) [NBP2-26651] - Analysis using the FITC conjugate of NBP2-26657. Staining using folate receptor 4 antibody. Staining of intracellular FoxP3 and cell surface folate receptor 4 with ...read more
Flow Cytometry: FOLR4 Antibody (TH6) [NBP2-26651] - Analysis using the PE conjugate of NBP2-26657. Staining using folate receptor 4 antibody. CD4/25+ gated mouse splenocytes probed using rat IgG2b isotype control ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
TH6
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated

Order Details

FOLR4 Antibody (TH6) Summary

Immunogen
CD3 mAb-stimulated CD4/25 T cells
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Rat
Gene
IZUMO1R
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10 - 1:1000
Publications
Read Publication using NBP2-26651.

Reactivity Notes

Mouse

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS containing 0.05% BSA.
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for FOLR4 Antibody (TH6)

  • folate receptor 4 (delta) homolog (mouse)
  • Folbp3
  • FOLR4
  • FR-delta
  • LOC390243
  • probable folate receptor delta

Background

Folates represent an important role in protein and nucleic acid biosynthesis and are recognized in particular for their role in spinal canal and brain development during early pregnancy. Recently, Yamaguchi et al, 2007 have shown that Folate receptor 4 (FR4), a subtype of the receptor for the vitamin folic acid is expressed at high levels in both natural and TGF-b-induced Treg cells. A majority of the CD4+ Tregs express Folate receptor 4 along with CD25 and FoxP3. In addition, there are functional similarities in regulating immune response by FoxP3 and FR4 expressing CD4+ Tregs which express CD25 as well. CD4+/25+FR4hi T cell population may be used as a functional immuno-suppressor Treg population which should express FoxP3. Folate receptor 4 may be considered as a surface marker for Tregs. The antibody produced by clones 12A5 and TH6 recognize FR4 in Tregs. FR4 is also known as folate receptor delta and folate-binding protein 3. FR4 antibody in combination with CD4/25 antibody may be used for isolation (both FACS and magnetic beads sorting) and staining of Tregs using simple surface staining while keeping the Tregs viable for subsequent down stream applications. Folate receptor 4 is known to be expressed exclusively in lymphoid tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FOLR4 Antibody (NBP2-26651)(1)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-26657AF350
Alexa Fluor 405 NBP2-26657AF405
Alexa Fluor 488 NBP2-26657AF488
Alexa Fluor 532 NBP2-26657AF532
Alexa Fluor 594 NBP2-26657AF594
Alexa Fluor 647 NBP2-26657AF647
Alexa Fluor 700 NBP2-26657AF700
Alexa Fluor 750 NBP2-26657AF750
DyLight 350 NBP2-26657UV
DyLight 405 NBP2-26657V
DyLight 488 NBP2-26657G
DyLight 550 NBP2-26657R
DyLight 594 NBP2-26651DL594
DyLight 650 NBP2-26657C
DyLight 680 NBP2-26657FR
DyLight 755 NBP2-26657IR
FITC NBP2-26657F
Janelia Fluor 549 NBP2-26657JF549
Janelia Fluor 646 NBP2-26657JF646
PE NBP2-26657PE
PerCP NBP2-26657PCP

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Array NBP2-26651

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Bioinformatics

Gene Symbol IZUMO1R