FOLR4 Antibody (12A5) [Allophycocyanin]

Images

 
Flow Cytometry: FOLR4 Antibody (12A5) [Allophycocyanin] [NBP2-26666] - Analysis of CD4+CD25+ gated mouse splenocytes using rat IgG2b isotype control (left) and NBP2-26666 (clone 12A5) (right) at 0.1 ug/10^6 cells.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
12A5
Clonality
Monoclonal
Host
Rat
Conjugate
Allophycocyanin

FOLR4 Antibody (12A5) [Allophycocyanin] Summary

Immunogen
CD3 mAb-stimulated CD4/CD25 T cells
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Rat
Gene
IZUMO1R
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1ul/1 million cells

Reactivity Notes

Mouse

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for FOLR4 Antibody (12A5) [Allophycocyanin]

  • folate receptor 4 (delta) homolog (mouse)
  • Folbp3
  • FOLR4
  • FR-delta
  • LOC390243
  • probable folate receptor delta

Background

Folates represent an important role in protein and nucleic acid biosynthesis and are recognized in particular for their role in spinal canal and brain development during early pregnancy. Recently, Yamaguchi et al, 2007 have shown that Folate receptor 4 (FR4), a subtype of the receptor for the vitamin folic acid is expressed at high levels in both natural and TGF-b-induced Treg cells. A majority of the CD4+ Tregs express FR4 along with CD25 and FoxP3. In addition, there are functional similarities in regulating immune response by FoxP3 and FR4 expressing CD4+ Tregs which express CD25 as well. CD4+CD25+FR4hi T cell population may be used as a functional immuno-suppressor Treg population which should express FoxP3. FR4 may be considered as a cell surface marker for Tregs. The antibodies produced by clones 12A5 and TH6 recognize FR4 in Tregs. FR4 is also known as folate receptor delta and folate-binding protein 3. The FR4 antibodies in combination with CD4 and CD25 antibodies may be used for isolation (both FACS and magnetic beads sorting) and staining of Tregs using simple surface staining while keeping the Tregs viable for subsequent down stream applications. FR4 is known to be expressed exclusively in lymphoid tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB5646
Species: Hu
Applications: WB, Flow, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, KO, ELISA(Sta)
NBP1-83435
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-49409
Species: Hu
Applications: IHC, IHC-P
NBP2-26666
Species: Mu
Applications: Flow
Supplier Logo

Publications for FOLR4 Antibody (NBP2-26666) (0)

There are no publications for FOLR4 Antibody (NBP2-26666).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for FOLR4 Antibody (NBP2-26666) (0)

There are no reviews for FOLR4 Antibody (NBP2-26666). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for FOLR4 Antibody (NBP2-26666) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-26652AF350
Alexa Fluor 532 NBP2-26652AF532
Alexa Fluor 594 NBP2-26652AF594
Alexa Fluor 750 NBP2-26652AF750
Allophycocyanin NBP2-26666
DyLight 350 NBP2-26652UV
DyLight 405 NBP2-26652V
DyLight 488 NBP2-26652G
DyLight 550 NBP2-26652R
DyLight 594 NBP2-26652DL594
DyLight 650 NBP2-26652C
DyLight 680 NBP2-26652FR
DyLight 755 NBP2-26652IR
FITC NBP2-26660
PerCP NBP2-26652PCP

Additional FOLR4 Products

Array NBP2-26666

Bioinformatics Tool for FOLR4 Antibody (NBP2-26666)

Discover related pathways, diseases and genes to FOLR4 Antibody (NBP2-26666). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for FOLR4 Antibody (NBP2-26666)

Discover more about diseases related to FOLR4 Antibody (NBP2-26666).

Blogs on FOLR4

There are no specific blogs for FOLR4, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our FOLR4 Antibody (12A5) [Allophycocyanin] and receive a gift card or discount.

Bioinformatics

Gene Symbol IZUMO1R