Cryptosporidium Parvum Antibody (7631) - BSA Free

• Reactivity: Pr
• Applications: ELISA, IHC
• Clone: 7631
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.1 mg/ml

Cryptosporidium Parvum Antibody (7631) - BSA Free Summary

• Immunogen: Intact oocysts of C.Parvum
• Specificity: NB100-65674 detects the protozoa Cryptosporidium parvum, an obligate intracellular parasite of the phylum Apicomplexa. The genome of C. parvum is one of the smallest among unicellular eukaryotic organisms. C. parvum is one of several species that cause cryptosporidiosis; a disease affecting the intestines of mammals and is spread through the fecal-oral route. The main symptom is self-limiting diarrhea in people with intact immune systems. However, in immunocompromised individuals, such as AIDS patients, infection can cause permanent & life-threatening diarrhea. Cryptosporidiosis is one of the most common waterborne diseases worldwide.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:20-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:50

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.1 mg/ml
• Purity: Protein A purified

Alternate Names for Cryptosporidium Parvum Antibody (7631) - BSA Free

• C. parvum

Background

Members of the genus Cryptosporidium are parasites of the intestinal tracts of fishes, reptiles, birds, and mammals. It seems that members of this genus do not display a high degree of host specificity, so the number of species in this genus remains a matter of some discussion. Cryptosporidium isolated from humans is now referred to as C. parvum. Cryptosporidium infections have been reported from a variety of wild and domesticated animals. Cryptosporidiosis is now recognized as an important opportunistic infection, especially in immunocompromised hosts. Cryptosporidium is a small protozoan parasite, measuring about 3-5 um. It lives on (or just under) the surface of the cells lining the small intestine, reproduces asexually, and oocysts are passed in the feces. Transmission of the infection occurs via the oocysts. Many human infections have been traced to the contamination of drinking water with oocysts from agricultural "run-off" (i.e., drainage from pastures), so it is considered a zoonosis. The most common symptom of cryptosporidiosis is watery diarrhea; other symptoms include stomach cramps or pain, fever, nausea and vomiting. In persons with healthy immune systems, symptoms usually last about 1 to 2 weeks.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cryptosporidium Parvum Antibody (NB100-65674)(2)

Publications using NB100-65674

• MOhAMED IMA, ElOSSIly N Evidences of brain and lung invasion of a local water Cryptosporidium parvum isolate in comparison to Iowa strain: serological and immunohistochemical cytokine evaluation Annals of Parasitology 2020-01-01 [PMID: 33128513] (IF/IHC, Mouse)
• Mansfield KG, Sasseville VG, Westmoreland SV. Molecular Localization Techniques in the Diagnosis and Characterization of NonHuman Primate Infectious Diseases. Vet Pathol. 2013-10-29 [PMID: 24168861] (IF/IHC, Protozoa)