Human Colon Tissue MicroArray (Rectal Cancer)

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 01. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 02. Rectum Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 03. Transverse Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 04. Transverse Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 05. Sigmoid Colon Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 06. Cecum Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 07. Cecum Mucinous Carcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 08. Sigmoid Colon Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 09. Descending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 10. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 11. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 12. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 13. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 14. Sigmoid Colon Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 15. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 16. Transverse Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 17. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 18. Cecum Mucinous Carcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 19. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - Cecum Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 21. Ascending Colon Mucinous Carcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 22. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 23. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 24. Transverse Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 25. Sigmoid Colon Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 26. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 27. Sigmoid Colon Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 28. Sigmoid Colon Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 29. Rectum Adenocarcinoma Well Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 30. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 31. Transverse Colon Mucinous Carcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 32. Rectum Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 33. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 34. Cecum Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 35. Descending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 36. Cecum Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 37. Transverse Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 38. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 39. Sigmoid Colon Adenocarcinoma Moderately Differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 40. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 41. Ascending Colon Adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 43. Ascending colon mucinous carcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 44. Transverse colon adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 45. Ascending colon adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 46. Sigmoid colon adenocarcinma, Moderately differentiated

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 47. Ascending colon adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 48. Rectum adenocarcinoma, M/D

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 50. Sigmoid adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 51. Sigmoid adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 52. Sigmoid adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 53. Rectum adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 54. Rectum adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 55. Ascending colon adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 56. Rectum, adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 57. Ascending colon, adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 59. Descending colon adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 58. Transverse colon adenocarcinoma

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 42. Sigmoid colon adenocarcinoma, well differentiated, T3N0M0, Stage II A

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 22. Cecum adenocarcinoma, moderately differentiated T3N0M0, Stage IIA

Hematoxylin & Eosin Stain: Human Colon Tissue MicroArray (Rectal Cancer) [NBP2-30256] - 49. Descending colon adenocarcinoma, moderately differentiated T3N0M0, Stage IIA

• Reactivity: Hu
• Applications: IHC

Human Colon Tissue MicroArray (Rectal Cancer) Summary

• Description: Microarray Panel:
  Colon and rectum cancer
  No. of samples: 59
  No. of patients: 59
  Core diameter: 2.0 mm
  Format: Formalin Fixed
  Section thickness: 4 micrometer
  Please see manual for tissue information and location.
  
  All tissues are fixed in 10% neutral buffered formalin for 12 to 24 hours, dehydrated with gradient ethanol, cleared with xylene, and embedded in paraffin. Then each slide is tested for immunohistochemistry on multiple antibodies including the p53 protein. Quality control is ensured as every tissue block is collected and arranged by certified pathologists, who used an identical process for their own research.
  
  About 100,000 cells are included in each sample with 2 mm core diameter. Some slides may have less than 60 cores due to sample loss when obtaining multiple sections. Maximum number of missing cores in a slide is less than 10%.

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.

Details for Array

• Type: Tissue
• Tissue Condition: Rectal Cancer

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Tissue Micro Arrays are guaranteed for 1 year from date of receipt.

Publications for Colon Tissue Micro Array (NBP2-30256)(8)

Publications using NBP2-30256

• Al-mousawi H, O’Mara M, Stewart G Identification of the HT-29 cell line as a model for investigating MCT1 transporters in sigmoid colon adenocarcinoma Biochemical and Biophysical Research Communications 2020-08-01 [PMID: 32703414] (IHC-P, Human)
• Ubillos L, Berriel E, Mazal D et al. Polypeptide-GalNAc-T6 expression predicts better overall survival in patients with colon cancer. Oncol Lett. 2018-07-01 [PMID: 29928405] (IHC-P, Human)
• Meisenberg C, Gilbert DC, Chalmers A et al. Clinical and cellular roles for TDP1 and TOP1 in modulating colorectal cancer response to irinotecan. Mol. Cancer Ther. 2014-12-18 [PMID: 25472594] (IHC-P)
  
  Details:
  Human Colon Tissue Microarray (Rectal Cancer) was used for IHC-P staining of TDP1 (NB100-81642 from Novus Biologicals, 1:200 dilution) and TOP1 proteins (Figure 2).
• Ralhan R, He HC, So AK et al. Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers. PLoS One. 2010-11-30 [PMID: 21152431] (IHC-P)
  
  Details:
  Breast cancer and adjacent normal (IMH-371), prostate cancer and adjacent normal (IMH-303), lung cancer (IMH-305), colon and rectal cancer (IMH-306), common cancers (IMH-327). IHC (paraffin): Tissues were labeled with EpEx and EpCAM antibodies, Figs 1, 3, 4, 6 & 7.
• Koller FL, Hwang DG, Dozier EA et al. Epithelial interleukin-4 receptor expression promotes colon tumor growth. Carcinogenesis. 2010-06-01 [PMID: 20176658]
• Fang C, Dean J, Smith JW. A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma. Cancer Res. 2007-10-01 [PMID: 17909007] (IHC-P)
  
  Details:
  IHC-paraffin]: 1. IMH-306 (Colon and rectal cancer) Fig. 5 2. IMH-339 (Colon and rectal, matching normal adjacent tissues of IMH-306) Fig. 5
• O'Toole JM, Rabenau KE, Burns K et al. Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member. Cancer Res. 2006-09-15 [PMID: 16982759] (IHC-P)
  
  Details:
  IHC-paraffin: 1. IMH-364 (breast tissue microarray) Fig. 1 2. IMH-305 (lung tissue microarray) Fig. 1 3. IMH-303 (prostate tissue microarray) Fig. 1.
• Adkins HB, Bianco C, Schiffer SG et al. Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo. J Clin Invest. 2003-08-01 [PMID: 12925698] (IHC-P)
  
  Details:
  IHC (paraffin): Fig. 1d.