beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody

Product Discontinued

beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody Summary

• Immunogen: B3GAT3 (NP_036332, 236 a.a. ~ 336 a.a) partial recombinant protein with GST tag.VVGFHTAWEPSRPFPVDMAGFAVALPLLLDKPNAQFDSTAPRGHLESSLLSHLVDPKDLEPRAANCTRVLVWHTRTEKPKMKQEEQLQRQGRGSDPAIEV
• Specificity: B3GAT3 - beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: B3GAT3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 22674034).

Reactivity Notes

Human. Mouse reactivity reported in scientific literature (PMID: 22674034). Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody

• B3GAT3
• beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
• Beta-1,3-glucuronyltransferase 3
• EC 2.4.1.135
• galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3
• GLCATI
• GlcAT-I
• GlcUAT-I
• Glucuronosyltransferase I
• Sqv-8-like protein
• UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase

Background

The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for beta-1,3-Glucuronyltransferase 3/B3GAT3 Antibody (H00026229-A01)(2)

Publications using H00026229-A01

• Wu Qianghua, Wang Jianru, Skubutyte Renata et al. Smad3 controls B-1,3-glucuronosyltransferase 1 expression in Rat nucleus pulposus cells: implications of dysregulated expression in disc disease. Arthritis and Rheumatism 2012-01-01 [PMID: 22674034] (ICC/IF, Mouse)
• Gogate SS, Nasser R, Shapiro IM, Risbud MV. Hypoxic regulation of [beta]1,3 glucuronosyl transferase-I (GlcAT-I) expression in nucleus pulposus cells of the intervertebral disc: Role of HIF proteins. Arthritis Rheum. 2011-03-11 [PMID: 21400481]

Bioinformatics

• Gene Symbol: B3GAT3
• Entrez:
  • 26229(Human)
• OMIM:
  • 606374(Human)
• Uniprot:
  • NP_036332(Human)