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HAF017). Specific bands were detected for NF kappa B1 at approximately 50 and 105 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. Thebcl-2promoter was detected by standard PCR. This application has not been tested in mouse samples." class="big_lightbox" target="_blank">
Species: Hu, Mu Applications: WB, ChIP Host: Goat Polyclonal
HAF007). A specific band was detected for NF kappa B1 at approximately 50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 4." class="big_lightbox" target="_blank">
Nuclear factor kappa beta (NFKB) is a transcription factor that is highly influenced by stress, free-radicals, UV light and hypoxia. Unsurprisingly, NFKB is essential for many human cancers, as it regulates the expression of many downstream proteins that regulate or modify cellular growth and development. NFKB effects on angiogenic pathways and reactive mechanisms to stress and damage are well established throughout literature. Atherosclerosis is partly attributed to the mis-regulation of NFKB in hypoxia. Arthritis is related to inflammation proteins regulated through NFKB. It also has been shown to be important in synapses in brain, leading to memory and cognitive ability or impairment. In all, NFKB is one of the fastest responding transcription factors in humans, and is likely to mediate many responsive events in diseases and injury recovery.
![Western Blot NFkB1/NFkB p105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/NFkB1_AF2697_Western_Blot_5210.jpg)
![Chromatin Immunoprecipitation (ChIP) NFkB1/NFkB p105 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/NFkB1_AF2697_Chromatin_Immunoprecipitation_11230.jpg)
