Species: Hu, Pm
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Pm
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Pm
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotesmitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed,activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin froman E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targetedsubstrates
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
79594 |
| Alternate Names |
- C1orf166mitochondrial E3 ubiquitin ligase 1
- E3 ubiquitin-protein ligase MUL1
- EC 6.3.2
- EC 6.3.2.-
- FLJ12875
- GIDERP11-401M16.2
- Growth inhibition and death E3 ligase
- MAPLE3 ubiquitin ligase
- mitochondrial E3 ubiquitin protein ligase 1
- mitochondrial ubiquitin ligase activator of NFKB 1
- mitochondrial ubiquitin ligase activator of NF-kB
- Mitochondrial-anchored protein ligase
- MULANchromosome 1 open reading frame 166
- Putative NF-kappa-B-activating protein 266
- RING finger protein 218
- RNF218mitochondria-anchored protein ligase
|
Research Areas for MUL1
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
Related MUL1 Blog Posts
Check out the latest blog posts on MUL1.
MUL1 - A Mito's best friend
MUL1 is an E3 ubiquitin-protein ligase with a RING finger domain that controls mitochondrial morphology, fragmentation and localization. E3 ubiquitin ligases accept the component ubiquitin from a donor E2 ubiquitin-conjugating directly transfer this u... Read more.
|
Read more MUL1 related blogs.
