FOX2 Products

Description

This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	23543 Human
Uniprot	NP_001026865.1 Human
Product By Gene ID	23543
Alternate Names	dJ106I20.3 Fox-1 homolog B fox-1 homologue FOX2Fox-2 fxh hexaribonucleotide binding protein 2 Hexaribonucleotide-binding protein 2 HRNBP2FOX-2 RBM9RTAHNRBP2 Repressor of tamoxifen transcriptional activity RNA binding motif protein 9 RNA binding protein fox-1 homolog 2 RNA binding protein, fox-1 homolog (C. elegans) 2 RNA-binding motif protein 9 RNA-binding protein 9

Research Areas for FOX2

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Cell Cycle and Replication