MAB9856
MAB1050, open histogram), followed by Allophycocyanin-conjugated Anti-Rabbit IgG Secondary Antibody (
F0111). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (
FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (
FC005). Staining was performed using our Staining Intracellular Molecules protocol." class="big_lightbox" target="_blank">
![Intracellular Staining by Flow Cytometry Factor V Antibody (2280A) [Unconjugated]](//images.novusbio.com/images/antibody/mab9856_human-coagulation-factor-v-mab-clone-2280a-intracellular-staining-by-flow-cytometry-662020194443.jpg)
Species: Hu
Applications: ELISA, CyTOF-ready, Flow
Host: Rabbit Monoclonal
MAB98563
DY990). Mouse Anti-Human Coagulation Factor V Monoclonal Antibody (Catalog #
MAB98562) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog #
DY998) followed by Substrate Solution (Catalog #
DY999) and stopping the enzymatic reaction with Stop Solution (Catalog #
DY994)." class="big_lightbox" target="_blank">
![ELISA Factor V Antibody (986243) [Unconjugated]](//images.novusbio.com/images/antibody/Coagulation_Factor_V_MAB98563_ELISA_23653.jpg)
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
MAB98562
MAB98563) coated on a Clear Polystyrene Microplate (Catalog #
DY990). Mouse Anti-Human Coagulation Factor V Monoclonal Antibody (Catalog # MAB98562) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog #
DY998) followed by Substrate Solution (Catalog #
DY999) and stopping the enzymatic reaction with Stop Solution (Catalog #
DY994)." class="big_lightbox" target="_blank">
![ELISA Factor V Antibody (986237) [Unconjugated]](//images.novusbio.com/images/antibody/Coagulation_Factor_V_MAB98562_ELISA_23652.jpg)
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Description
The F5 gene encodes a 2,224 amino acid long, 251 kDA coagulation factor V protein that is critical in the regulation of homeostasis. Additionally, F5 functions as a cofactor for the prothrombinase activity of factor Xa which results in the initiation of prothrombin to thrombin. F5 participates in blood coagulation signaling pathways, the blood clotting cascade, platelet degranulation as well as activation, signaling, and aggregation, and in responses to elevated platelet cytosolic Ca2+. It interacts with genes PROC, PROS1, F2, MMRN1, and CALR. Defects in F5 cause factor 5 deficiency (owren parahemophilia), thrombophilia due to activated protein C resistance, susceptibility to Budd-Chiari syndrome, susceptibility to ischemic strokes, and susceptibility to pregnancy loss, recurrent, type 1. F5 is also linked to deep vein thrombosis, antithrombin III deficiency, retinal vein occlusion, legg-calve-perthes disease, liver disease, hypertension, pulmonary embolism, lupus, and patent foramen ovale.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
2153 |
| Alternate Names |
- Activated protein C cofactor
- coagulation factor V (proaccelerin, labile factor)
- coagulation factor V jinjiang A2 domain
- coagulation factor V
- factor V Leiden
- FVL
- PCCF
- Proaccelerin, labile factor
|
![Intracellular Staining by Flow Cytometry Factor V Antibody (2280A) [Unconjugated]](http://images.novusbio.com/images/antibody/mab9856_human-coagulation-factor-v-mab-clone-2280a-intracellular-staining-by-flow-cytometry-662020194443.jpg)
![ELISA Factor V Antibody (986243) [Unconjugated]](http://images.novusbio.com/images/antibody/Coagulation_Factor_V_MAB98563_ELISA_23653.jpg)
![ELISA Factor V Antibody (986237) [Unconjugated]](http://images.novusbio.com/images/antibody/Coagulation_Factor_V_MAB98562_ELISA_23652.jpg)
