ZCCHC11/TUT4 Products

Antibodies
ZCCHC11/TUT4 Antibody
ZCCHC11/TUT4 Antibody
NB100-783
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
ZCCHC11/TUT4 Antibody
ZCCHC11/TUT4 Antibody
NBP1-83026
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ZCCHC11/TUT4 Antibody
ZCCHC11/TUT4 Antibody
NBP2-27539
Species: Mu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
ZCCHC11/TUT4 Overexpression L ...
ZCCHC11/TUT4 Overexpression Lysate...
H00023318-T01
Species: Hu
Applications: WB
Proteins
ZCCHC11/TUT4 Recombinant Prot ...
ZCCHC11/TUT4 Recombinant Protein
H00023318-P01
Species: Hu
Applications: WB, ELISA, PA
ZCCHC11/TUT4 Recombinant Prot ...
ZCCHC11/TUT4 Recombinant Protein A...
NBP1-83027PEP
Species: Hu
Applications: AC
ZCCHC11/TUT4 Recombinant Prot ...
ZCCHC11/TUT4 Recombinant Protein A...
NBP1-83026PEP
Species: Hu
Applications: AC
RNAi
ZCCHC11/TUT4 RNAi
ZCCHC11/TUT4 RNAi
H00023318-R02
Species: Hu
ZCCHC11/TUT4 RNAi
ZCCHC11/TUT4 RNAi
H00023318-R01
Species: Hu
ZCCHC11/TUT4 RNAi
ZCCHC11/TUT4 RNAi
H00023318-R03
Species: Hu

Description

Uridylyltransferase that acts as a suppressor of microRNA (miRNA) biogenesis by specifically mediating the terminal uridylation of some miRNAs. Catalyzes the 3' uridylation of precursor let-7 (pre-let-7), a miRNA precursor. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cells and is required for ES cells to maintain pluripotency. Does not bind RNA by itself, recruited to pre-let-7 miRNAs via its interaction with LIN28 and LIN28B. Also catalyzes the 3' uridylation of miR-26A, a miRNA that represses IL6 transcript, leading to abrogate IL6 transcript repression and promote cytokine expression. May also suppress Toll-like receptor-induced NF-kappa-B activity via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 23318
Alternate Names
  • TUTase 4
  • EC 2.7.7.52
  • TUT4
  • terminal uridylyltransferase 4
  • Zinc finger CCHC domain-containing protein 11
  • PAP associated domain containing 3
  • PAPD3
  • KIAA0191FLJ42878
  • DKFZp779C1943
  • zinc finger, CCHC domain containing 11

Pathways for ZCCHC11/TUT4

View related products by pathway and learn more about each of the pathways below.

Immune Response
Dna Replication
Cell Proliferation
Cell Cycle
S Phase
Innate Immune Response
Cell Differentiation
Stem Cell Maintenance
Rna Interference

Research Areas for ZCCHC11/TUT4

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for ZCCHC11/TUT4

Learn more about PTMs related to ZCCHC11/TUT4.

Cleavage

Bioinformatics Tool for ZCCHC11/TUT4

Discover related pathways, diseases and genes to ZCCHC11/TUT4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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