ZAK Products

Antibodies
ZAK Antibody (3G5)
ZAK Antibody (3G5)
H00051776-M03
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
ZAK Antibody
ZAK Antibody
NBP1-33137
Species: Hu, Mu, Bv
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ZAK Antibody (3D11)
ZAK Antibody (3D11)
H00051776-M02
Species: Hu
Applications: WB, ELISA, ICC/IF, S-ELISA
Host: Mouse Monoclonal
Lysates
ZAK Overexpression Lysate
ZAK Overexpression Lysate
NBL1-17956
Species: Hu
Applications: WB
ZAK Overexpression Lysate
ZAK Overexpression Lysate
NBP2-09880
Species: Hu
Applications: WB
ZAK Overexpression Lysate
ZAK Overexpression Lysate
NBP2-07004
Species: Hu
Applications: WB
Proteins
Recombinant Human ZAK GST (N- ...
Recombinant Human ZAK GST (N-Term)...
H00051776-P01
Species: Hu
Applications: WB, ELISA, PA, AP, KA
Recombinant Human ZAK GST (N- ...
Recombinant Human ZAK GST (N-Term)...
H00051776-Q01
Species: Hu
Applications: WB, ELISA, PA, AP

Description

ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 51776
Alternate Names
  • EC 2.7.11
  • Mixed lineage kinase-related kinase
  • MLT
  • EC 2.7.11.25
  • MLK7
  • sterile alpha motif and leucine zipper containing kinase AZK
  • AZK
  • protein kinase
  • MLTK
  • pk
  • MLK-related kinase
  • mlklak
  • MLK-like mitogen-activated protein triple kinase
  • mixed lineage kinase-related kinase MRK-beta
  • HCCS-4
  • mixed lineage kinase with a leucine zipper and a sterile alpha motif
  • Sterile alpha motif- and leucine zipper-containing kinase AZK
  • mixed lineage kinase 7
  • Leucine zipper- and sterile alpha motif-containing kinase
  • mitogen-activated protein kinase kinase kinase MLT
  • Human cervical cancer suppressor gene 4 protein
  • MRKcervical cancer suppressor gene 4 protein

Research Areas for ZAK

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for ZAK

Learn more about PTMs related to ZAK.

Phosphorylation
Methylation
Demethylation

Bioinformatics Tool for ZAK

Discover related pathways, diseases and genes to ZAK. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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