ZAK Products

Antibodies
ZAK Antibody
ZAK Antibody
NBP1-90367
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ZAK Antibody (3G5)
ZAK Antibody (3G5)
H00051776-M03
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
ZAK Antibody
ZAK Antibody
NBP1-33137
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ZAK Overexpression Lysate (Na ...
ZAK Overexpression Lysate (Native)
NBP2-07004
Applications: WB
ZAK Overexpression Lysate (Na ...
ZAK Overexpression Lysate (Native)
NBL1-17956
Applications: WB
ZAK Overexpression Lysate (Na ...
ZAK Overexpression Lysate (Native)
NBP2-09880
Applications: WB
Proteins
ZAK Recombinant Protein
ZAK Recombinant Protein
H00051776-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
ZAK Partial Recombinant Prote ...
ZAK Partial Recombinant Protein
H00051776-Q01
Species: Hu
Applications: WB, ELISA, PA
ZAK Recombinant Protein Antig ...
ZAK Recombinant Protein Antigen
NBP1-90367PEP
Species: Hu
Applications: AC
RNAi
ZAK RNAi
ZAK RNAi
H00051776-R04
Species: Hu
ZAK RNAi
ZAK RNAi
H00051776-R03
Species: Hu

Description

ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 51776
Alternate Names
  • EC 2.7.11
  • Mixed lineage kinase-related kinase
  • MLT
  • EC 2.7.11.25
  • MLK7
  • sterile alpha motif and leucine zipper containing kinase AZK
  • AZK
  • protein kinase
  • MLTK
  • pk
  • MLK-related kinase
  • mlklak
  • MLK-like mitogen-activated protein triple kinase
  • mixed lineage kinase-related kinase MRK-beta
  • HCCS-4
  • mixed lineage kinase with a leucine zipper and a sterile alpha motif
  • Sterile alpha motif- and leucine zipper-containing kinase AZK
  • mixed lineage kinase 7
  • Leucine zipper- and sterile alpha motif-containing kinase
  • mitogen-activated protein kinase kinase kinase MLT
  • Human cervical cancer suppressor gene 4 protein
  • MRKcervical cancer suppressor gene 4 protein

Research Areas for ZAK

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for ZAK

Learn more about PTMs related to ZAK.

Phosphorylation
Methylation
Demethylation

Bioinformatics Tool for ZAK

Discover related pathways, diseases and genes to ZAK. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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