YARS Products

Description

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

Bioinformatics

Entrez	287924 Rat 8565 Human
Uniprot	AAH01933 Human AAH04151 Human AAH16689 Human NM_003680 Human NP_003671 Human
Product By Gene ID	8565
Alternate Names	CMTDIC EC 6.1.1 EC 6.1.1.1 Tyrosyl--tRNA ligase tyrosyl-tRNA synthetase tyrosyl-tRNA synthetase, cytoplasmic TyrRS TYRRS YRStyrRS YTStyrosine tRNA ligase 1, cytoplasmic