XRCC3 Products

Antibodies
Antibody Pairs
XRCC3 Antibody Pair
XRCC3 Antibody Pair
H00007517-PW1
Species: Hu
Applications: WB, IP
Lysates
XRCC3 Overexpression Lysate ( ...
XRCC3 Overexpression Lysate (Denat...
H00007517-T01
Species: Hu
Applications: WB
XRCC3 Overexpression Lysate ( ...
XRCC3 Overexpression Lysate (Native)
NBL1-17915
Applications: WB
XRCC3 Overexpression Lysate ( ...
XRCC3 Overexpression Lysate (Native)
NBP2-09327
Applications: WB
Proteins
XRCC3 Recombinant Protein Ant ...
XRCC3 Recombinant Protein Antigen
NBP2-49636PEP
Species: Hu
Applications: AC
XRCC3 Recombinant Protein
XRCC3 Recombinant Protein
NBP2-22953
Species: Hu
Applications: PAGE
RNAi
XRCC3 RNAi
XRCC3 RNAi
H00007517-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

XRCC3, also known as DNA repair protein XRCC3, X-ray repair cross-complementing protein 3, and CMM6, belongs to the RecA family and the RAD51 subfamily. XRCC3 plays a role in the homologous recombination repair (HRR) pathway of double-stranded DNA. The pathway is responsible for repairing chromosomal fragmentation, translocations, and deletions. Additionally, XRCC3 is also involved in regulating the mitochondrial DNA copy number in the presence of oxidative stress in the presence of RAD51 and RAD51C. XRCC3 is a functional compliment to Chinese hamster irs1SF. Rare microsatellite polymorphisms in the XRCC3 gene have been associated with cancer in patients with radiosensitivity. Defects of the XRCC3 gene have also been linked to breast cancer and cutaneous malignant melanoma type 6 (CMM6).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 7517
Alternate Names
  • DNA repair protein XRCC3
  • CMM6
  • X-ray repair cross-complementing protein 3
  • X-ray repair complementing defective repair in Chinese hamster cells 3

Research Areas for XRCC3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Chemokine Research
DNA Repair
Genes Sensitive to DNA Damaging Agents
Homologous Recombination
Tumor Suppressors

PTMs for XRCC3

Learn more about PTMs related to XRCC3.

Phosphorylation
Methylation
Acetylation
Oxidation

Bioinformatics Tool for XRCC3

Discover related pathways, diseases and genes to XRCC3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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