XAGE1D Products

Description

XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites.

Bioinformatics

Entrez	9503 Human
Uniprot	NP_065144 Human NP_597673 Human NP_597673.1 Human Q9HD64 Human
Product By Gene ID	9503
Alternate Names	cancer/testis associated protein CT12.1C CTP9 G antigen family D member 2 member 1c X antigen family, member 1C XAGE1

Research Areas for XAGE1D

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Tumor Suppressors