WSTF Products

Antibodies
WSTF Antibody
WSTF Antibody
NB600-279
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
WSTF Antibody (5E9.)
WSTF Antibody (5E9.)
H00009031-M01
Species: Hu
Applications: ELISA, IHC-P, PLA
Host: Mouse Monoclonal
WSTF Antibody
WSTF Antibody
NBP2-57741
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Proteins
Recombinant Human WSTF Protei ...
Recombinant Human WSTF Protein
H00009031-Q01
Species: Hu
Applications: WB, ELISA, PA
WSTF Recombinant Protein Anti ...
WSTF Recombinant Protein Antigen
NBP2-57741PEP
Species: Hu
Applications: AC
RNAi
WSTF RNAi
WSTF RNAi
H00009031-R01
Species: Hu
Applications: RNAi, RNAi SP
WSTF RNAi
WSTF RNAi
H00009031-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The Williams Syndrome Transcription Factor (WSTF), the product of the WBSCR9 gene, is invariably deleted in the haploinsufficiency Williams-Beuren Syndrome. Along with the nucleosome-dependent ATPase ISWI, WSTF forms a novel chromatin remodeling complex, WICH (WSTF-ISWI chromatin remodeling complex). WSTF binds stably to mitotic chromosomes. As dysfunction of other chromatin remodeling factors often has severe effects on development, haploinsufficiency of WSTF may explain some of the phenotypes associated with this disease (1). Evidence has shown that the WSTF is targeted to replication foci through direct interaction with the DNA clamp PCNA, an important coordinator of DNA and chromatin replication. WSTF, in turn, recruits ISWI-type nucleosome-remodelling factor SNF2H to replication sites. It has been proposed that the WSTF-ISWI complex has a role in the maintenance of chromatin structures during DNA replication (2).

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 9031
Alternate Names
  • williams-Beuren syndrome chromosomal region 10 protein
  • bromodomain adjacent to zinc finger domain, 1B

Research Areas for WSTF

Find related products by research area and learn more about each of the different research areas below.

Transcription Factors and Regulators

Bioinformatics Tool for WSTF

Discover related pathways, diseases and genes to WSTF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.