Hu, Mu, RtApplications:
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Monoclonal
Applications: WB, ELISA, PA, AP
WNK lysine deficient protein kinase 1 (WNK1) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. WNK1 is responsible for controling Na+ and Cl- ion transport by inhibiting the activity of other related protein kinases, such as WNK4.
WNK1 mutations have been associated with Gordon hyperkalemia-hypertension syndrome (pseudohypoaldosteronism type II) and congenital sensory neuropathy.
WNK1 is also known as Human Accelerated Region 5, and is thought to have played a key role in differentiating humans from apes.
|Product By Gene ID
- EC 2.7.11
- Kinase deficient protein
- Protein kinase with no lysine 1
- Protein kinase lysine-deficient 1
- serine/threonine-protein kinase WNK1
- Erythrocyte 65 kDa protein
- prostate-derived sterile 20-like kinase
- protein kinase, lysine deficient 1
- HSAN2hereditary sensory neuropathy, type II
- EC 220.127.116.11
- WNK lysine deficient protein kinase 1
Bioinformatics Tool for WNK1
Discover related pathways, diseases and genes to WNK1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.