WHSC2 Products

Antibodies
WHSC2 Antibody (6B11H8)
WHSC2 Antibody (6B11H8)
Species: Hu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
WHSC2 Antibody
WHSC2 Antibody
H00007469-B03P
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
WHSC2 Antibody
WHSC2 Antibody
NBP1-05975
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
WHSC2 Overexpression Lysate ( ...
WHSC2 Overexpression Lysate (Denat...
H00007469-T01
Species: Hu
Applications: WB
WHSC2 Overexpression Lysate ( ...
WHSC2 Overexpression Lysate (Native)
NBP2-07719
Applications: WB
Proteins
WHSC2 Recombinant Protein Ant ...
WHSC2 Recombinant Protein Antigen
NBP2-38454PEP
Species: Hu
Applications: AC
WHSC2 Recombinant Protein
WHSC2 Recombinant Protein
NBP1-50940
Applications: PAGE
RNAi
WHSC2 RNAi
WHSC2 RNAi
H00007469-R01
Species: Hu

Description

WHSC2 is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 7469
Alternate Names
  • negative elongation factor A
  • NELFA
  • Wolf-Hirschhorn syndrome candidate 2 protein
  • NELF-AFLJ25112
  • FLJ10442
  • Wolf-Hirschhorn syndrome candidate 2

Pathways for WHSC2

View related products by pathway and learn more about each of the pathways below.

Transport
Dna Replication
Cell Cycle
Hypersensitivity
Chromatin Assembly
Oncogenesis

Research Areas for WHSC2

Find related products by research area and learn more about each of the different research areas below.

Cancer

Bioinformatics Tool for WHSC2

Discover related pathways, diseases and genes to WHSC2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.