Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bv, RM, Xp, Ze
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
VPS4A is encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18. [provided by RefSeq]
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human |
Product By Gene ID |
27183 |
Alternate Names |
- FLJ22197
- hVPS4
- Protein SKD2
- SKD1
- SKD1A
- SKD2
- vacuolar protein sorting 4 homolog A (S. cerevisiae)
- vacuolar protein sorting 4A (yeast homolog)
- vacuolar protein sorting factor 4A
- vacuolar protein sorting-associated protein 4A
- vacuolar sorting protein 4
- VPS4-1SKD1-homolog
- VPS4vacuolar protein sorting 4A (yeast)
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Research Areas for VPS4A
Find related products by research area and learn more about each of the different research areas below.
Protein Phosphatase