VKORC1 Products

Antibodies
VKORC1 Antibody
VKORC1 Antibody
NBP1-92573
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
VKORC1 Overexpression Lysate ...
VKORC1 Overexpression Lysate (Native)
NBL1-17727
Applications: WB
VKORC1 Overexpression Lysate ...
VKORC1 Overexpression Lysate (Native)
NBP2-10124
Applications: WB
Proteins
VKORC1 Recombinant Protein
VKORC1 Recombinant Protein
H00079001-P01
Species: Hu
Applications: WB, ELISA, PA
VKORC1 Recombinant Protein An ...
VKORC1 Recombinant Protein Antigen
NBP1-92573PEP
Species: Hu
Applications: AC

Description

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 79001
Alternate Names
  • EDTP308
  • vitamin K1 epoxide reductase (warfarin-sensitive)
  • VKCFD2
  • vitamin K epoxide reductase complex subunit 1
  • FLJ00289
  • phylloquinone epoxide reductase
  • EC 1.1.4.1
  • MST576
  • Vitamin K1 2,3-epoxide reductase subunit 1
  • vitamin K dependent clMST134
  • VKORMGC2694
  • IMAGE3455200
  • vitamin K epoxide reductase complex, subunit 1

PTMs for VKORC1

Learn more about PTMs related to VKORC1.

Carboxylation
Gamma-carboxylation
Reduction
Oxidation
Cleavage
Decarboxylation

Bioinformatics Tool for VKORC1

Discover related pathways, diseases and genes to VKORC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.