VAChT/SLC18A3 Products

Antibodies
VAChT/SLC18A3 Antibody
VAChT/SLC18A3 Antibody
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
VAChT/SLC18A3 Antibody
VAChT/SLC18A3 Antibody
NB100-91347
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
VAChT/SLC18A3 Antibody
VAChT/SLC18A3 Antibody
NB110-74764
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Goat Polyclonal
Lysates
VAChT/SLC18A3 Overexpression ...
VAChT/SLC18A3 Overexpression Lysat...
NBP2-10859
Applications: WB
Proteins
VAChT/SLC18A3 Partial Recombi ...
VAChT/SLC18A3 Partial Recombinant ...
H00006572-Q01
Species: Hu
Applications: WB, ELISA, PA
VAChT/SLC18A3 Recombinant Pro ...
VAChT/SLC18A3 Recombinant Protein
H00006572-G01-10ug
Species: Hu
VAChT/SLC18A3 Peptide
VAChT/SLC18A3 Peptide
NB100-91348PEP
Species: Hu
Applications: AC
RNAi
VAChT/SLC18A3 RNAi
VAChT/SLC18A3 RNAi
H00006572-R01
Species: Hu

Description

Vesicular Acetylcholine Transporter (VAChT), (approx. 70kD protein), belongs to the family of vesicular monoamine transporters(VMATs), which include VMAT1 and VMAT2 and the C.elegans putative ACh transporter unc-17. Members of this family function to concentrate neurotransmitters into synaptic vesicles through exchange of protons for neurotransmitters. VAChT is a functional transporter for the neurotransmitter acetylcholine(ACh). ACh is synthesized in the cytoplasm by choline acetyl transferase (ChAT) and transported by VAChT into synaptic vesicles where it is stored until released. After release from presynaptic nerve terminals ACh is hydrolyzed by extracellular ACh-esterases(AChE) to choline and acetate. VAChT mRNA is expressed in all known major cholinergic neurons in the central and peripheral nervous system. VAChT is abundantly expressed in the CNS and is mainly localized in small synaptic vesicles in cholinergic nerve terminals. VAChT provides a specific marker for cholinergic neurons for the study of cholinergic transmission in experimental models, in Alzheimer's disease and other nervous system disorders.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Rat
Product By Gene ID 6572
Alternate Names
  • MGC12716
  • VAChT
  • Solute carrier family 18 member 3
  • VACHTvesicular acetylcholine transporter
  • solute carrier family 18, member 3
  • solute carrier family 18 (vesicular acetylcholine), member 3

PTMs for VAChT/SLC18A3

Learn more about PTMs related to VAChT/SLC18A3.

Phosphorylation
Phosphorothioation
Reduction
Cleavage
Dephosphorylation

Bioinformatics Tool for VAChT/SLC18A3

Discover related pathways, diseases and genes to VAChT/SLC18A3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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