USP18 Products

Antibodies
USP18 Antibody
USP18 Antibody
NBP1-92566
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
USP18 Antibody
USP18 Antibody
NBP1-33675
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
USP18 Antibody
USP18 Antibody
H00011274-B02P
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Antibody Pairs
USP18 Antibody Pair
USP18 Antibody Pair
H00011274-PW1
Species: Hu
Applications: WB, IP
Lysates
USP18 Overexpression Lysate ( ...
USP18 Overexpression Lysate (Denat...
H00011274-T01
Species: Hu
Applications: WB
USP18 Overexpression Lysate ( ...
USP18 Overexpression Lysate (Native)
NBL1-17648
Applications: WB
Proteins
USP18 Recombinant Protein
USP18 Recombinant Protein
H00011274-P01
Species: Hu
Applications: WB, ELISA, PA
USP18 Partial Recombinant Pro ...
USP18 Partial Recombinant Protein
H00011274-Q01
Species: Hu
Applications: WB, ELISA, PA
USP18 Recombinant Protein Ant ...
USP18 Recombinant Protein Antigen
NBP1-92566PEP
Species: Hu
Applications: AC
RNAi
USP18 RNAi
USP18 RNAi
H00011274-R01
Species: Hu

Description

UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 11274
Alternate Names
  • EC 3.1.2.15
  • hUBP43
  • EC 3.4.19.-
  • ubl thioesterase 18,43 kDa ISG15-specific protease
  • Ubl thiolesterase 18
  • ubl carboxyl-terminal hydrolase 18
  • ubiquitin specific protease 18
  • ISG43UBP43
  • ISG15-specific-processing protease
  • ubiquitin specific peptidase 18

Research Areas for USP18

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Neuroscience
Ubiquitin Proteasome Pathway

PTMs for USP18

Learn more about PTMs related to USP18.

Isgylation
Phosphorylation
Cleavage
Ubiquitination
Reduction
Methylation

Bioinformatics Tool for USP18

Discover related pathways, diseases and genes to USP18. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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