Uromodulin Products

Antibodies
Uromodulin Antibody (774056)
Uromodulin Antibody (774056)
MAB5175
Species: Mu
Applications: WB, IHC
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
Uromodulin Antibody (10.32)
Uromodulin Antibody (10.32)
NBP1-50321
Species: Hu, Ca
Applications: IHC, IHC-Fr, IHC-P, ICC/IF
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Uromodulin Antibody
Uromodulin Antibody
AF5175
Species: Mu
Applications: WB, IHC
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
ELISA Kits
Human Uromodulin DuoSet ELISA ...
Human Uromodulin DuoSet ELISA, 5 P...
DY5144-05
Species: Hu
Applications: ELISA
Mouse Uromodulin ELISA Kit (C ...
Mouse Uromodulin ELISA Kit (Colori...
NBP2-82437
Species: Mu
Applications: ELISA
Rat Uromodulin ELISA Kit (Col ...
Rat Uromodulin ELISA Kit (Colorime...
NBP2-82457
Species: Rt
Applications: ELISA
Lysates
Uromodulin 293T Cell Transien ...
Uromodulin 293T Cell Transient Ove...
H00007369-T01
Species: Hu
Applications: WB
Uromodulin 293T Cell Transien ...
Uromodulin 293T Cell Transient Ove...
H00007369-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human Uromodulin ...
Recombinant Human Uromodulin GST (...
H00007369-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Uromodulin Recombinant Protei ...
Uromodulin Recombinant Protein Ant...
NBP2-33730PEP
Species: Hu
Applications: AC
Uromodulin Recombinant Protei ...
Uromodulin Recombinant Protein Ant...
NBP2-33393PEP
Species: Hu
Applications: AC

Description

Uromodulin encodes uromodulin, the most abundant protein in normal urine. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. Uromodulin may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of uromodulin in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the autosomal dominant renal disorders medullary cystic kidney disease-2 (MCKD2) and familial juvenile hyperuricemic nephropathy (FJHN). These disorders are characterized by juvenile onset of hyperuricemia, gout, and progressive renal failure. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7369
Alternate Names
  • HNFJ1
  • uromucoid
  • FJHN
  • Tamm-Horsfall glycoprotein
  • ADMCKD2
  • THGP
  • THP
  • Tamm-Horsfall urinary glycoprotein
  • HNFJ
  • uromodulin (uromucoid, Tamm-Horsfall glycoprotein)
  • MCKD2
  • uromodulin

Research Areas for Uromodulin

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for Uromodulin

Discover related pathways, diseases and genes to Uromodulin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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