Hu, Mu, CaApplications:
ICC/IF, IHC, IHC-P, PEP-ELISAHost:
Applications: Binding Activity
UNC5C is a gene that codes for a protein that is the receptor for netrin that is required for axon guidance, as it mediates the axon repulsion of neuronal growth cones when there is ligand binding in the nervous system, and can also help to induce apoptosis. The protein encoded by UNC5C has two isoforms, with lengths of 931 and 597 amino acids and weights of approximately 103 and 66 kDa respectively. Current studies are being done on diseases and disorders related to this gene including colorectal cancer, renal cell carcinoma, rheumatoid arthritis, Parkinson's disease, kidney cancer, colon cancer, osteoarthritis, schizophrenia, and neuronitis. UNC5C has also been shown to have interactions with NTN1, PTPN11, DAPK1, DCC, and FYN in pathways such as the netrin signaling and axon guidance pathways.
|Product By Gene ID
- unc-5 homolog 3
- Protein unc-5 homolog 3
- netrin receptor UNC5C
- UNC5H3unc5 (C.elegans homolog) c
- Protein unc-5 homolog C
- unc-5 homolog C (C. elegans)
Research Areas for UNC5H3/UNC5C
Find related products by research area and learn more about each of the different research areas below.Apoptosis
Bioinformatics Tool for UNC5H3/UNC5C
Discover related pathways, diseases and genes to UNC5H3/UNC5C. Need help? Read the Bioinformatics Tool Guide
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