ULK1 Products

Antibodies
ULK1 Antibody
ULK1 Antibody
NBP2-24738
Species: Hu, Mu, Mk
Applications: WB, IHC-P
Host: Rabbit Polyclonal
ULK1 Antibody (JA58-36)
ULK1 Antibody (JA58-36)
NBP2-66765
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Monoclonal
ULK1 Antibody
ULK1 Antibody
NBP2-41217
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P, ICC/IF
Host: Rabbit Polyclonal
Lysates
ULK1 Overexpression Lysate
ULK1 Overexpression Lysate
NBL1-17607
Species: Hu
Applications: WB
Proteins
Recombinant Human ULK1 Protei ...
Recombinant Human ULK1 Protein
H00008408-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Recombinant Human ULK1 Protei ...
Recombinant Human ULK1 Protein
H00008408-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
ULK1 Recombinant Protein Anti ...
ULK1 Recombinant Protein Antigen
NBP2-56576PEP
Species: Hu
Applications: AC
RNAi
ULK1 RNAi
ULK1 RNAi
H00008408-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

ULK1 belongs to the serine/threonine protein kinase family. It is involved in axon growth and plays an essential role in neurite branching during sensory axon outgrowth. Knockdown of ULK1 results in impaired endocytosis of nerve growth factor (NGF), excessive axon arborization, and severely stunted axon elongation indicating that ULK1 mediates a non clathrin coated endocytosis in sensory growth cones. Knockdown of ULK1 also inhibits the autophagic response. It appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy related (Atg) proteins.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 8408
Alternate Names
  • EC 2.7.11
  • FLJ38455
  • Unc-51-like kinase 1
  • unc-51 (C. elegans)-like kinase 1
  • KIAA0722
  • UNC51
  • serine/threonine-protein kinase ULK1
  • EC 2.7.11.1
  • ATG1 autophagy related 1 homolog
  • ATG1A
  • Unc51.1
  • ATG1
  • FLJ46475
  • unc-51-like kinase 1 (C. elegans)

Research Areas for ULK1

Find related products by research area and learn more about each of the different research areas below.

Autophagy
mTOR Pathway
Protein Kinase

PTMs for ULK1

Learn more about PTMs related to ULK1.

Phosphorylation
Dephosphorylation
Acetylation
Cleavage
Methylation

Bioinformatics Tool for ULK1

Discover related pathways, diseases and genes to ULK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related ULK1 Blog Posts

Check out the latest blog posts on ULK1.
Animal Models to Study Autophagy
By Christina Towers, PhD What is autophagy?Autophagy is the catabolic process that degrades cytoplasmic material via the lysosome. In the beginning... the process of macroautophagy was originally characterized in...    Read more.
Best Methods to Induce and Inhibit Autophagy Pharmacologically
By Christina Towers, PhD Autophagy facilitates the degradation and recycling of damaged cytoplasmic material. The multistep process consists of a double membrane structure called an autophagosome that engulfs proteins...    Read more.

    Read more.
Autophagy independent roles of the core ATG proteins
By Christina Towers, PhD. Autophagy and ATG ProteinsAutophagy is a nutrient recycling process that cells use to fuel metabolism, particularly in response to nutrient deprivation.  It is critical for removal of dam...    Read more.
The Many Connections Between Autophagy and Kidney Disease
By Yoskaly Lazo-Fernandez, PhD The first description of what is called today an autophagosome was given in a paper published in 1957. Its author employed electron microscopy to observe the neonatal features of mous...    Read more.
VPS34 - autophagy initiator and regulator of endosomal trafficking
VPS34, vacuolar protein sorting 34, is the only identified Class III phosphoinositide-3 kinase (PI3K) in mammals and is ubiquitously expressed in all eukaryotic cells. VPS34 is a 100 kDa protein responsible for phosphorylating phosphatidylinositol...    Read more.
ULK1 - mammalian homologue of the yeast ATG1 kinase
Autophagy is an important cellular process involved in degradation and recycling of cellular macromolecules in response to stress or starvation. Autophagy is carried out in four main phases: phagophore nucleation, autophagosome elongation, docking...    Read more.
Read more ULK1 related blogs.