UBE2N/Ubc13 Products

Antibodies
UBE2N/Ubc13 Antibody
UBE2N/Ubc13 Antibody
NB100-56357
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
UBE2N/Ubc13 Antibody
UBE2N/Ubc13 Antibody
NBP1-76593
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UBE2N/Ubc13 Antibody
UBE2N/Ubc13 Antibody
AF8197
Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
Lysates
UBE2N/Ubc13 Overexpression Ly ...
UBE2N/Ubc13 Overexpression Lysate ...
NBL1-17541
Applications: WB
Proteins
UBE2N/Ubc13 Recombinant Prote ...
UBE2N/Ubc13 Recombinant Protein An...
NBP2-48823PEP
Species: Hu
Applications: AC
UBE2N/Ubc13 Peptide
UBE2N/Ubc13 Peptide
NBP1-96768
Applications: WB, ELISA, IP
UBE2N/Ubc13 Peptide
UBE2N/Ubc13 Peptide
NBP1-76593PEP
Species: Hu
Applications: AC
RNAi
UBE2N/Ubc13 RNAi
UBE2N/Ubc13 RNAi
H00007334-R01
Species: Hu

Description

UBC13 is a member of the E2 ubiquitin-conjugating enzyme family also known as Ubiquitin-conjugating enzyme E2 N, Ubiquitin-protein ligase N, Ubiquitin carrier protein N and Bendless-like ubiquitin-conjugating enzyme. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. UBC13 forms a heterodimer with UBE2V2 which then catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. UBC13 also mediates transcriptional activation of target genes and plays a role in the control of progress through the cell cycle and differentiation, as well as error-free DNA repair. UBC13 also contributes to the survival of cells after DNA damage.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 7334
Alternate Names
  • Ubiquitin-protein ligase N
  • Ubc13
  • Ubiquitin carrier protein N
  • BLU
  • Bendless-like ubiquitin-conjugating enzyme
  • yeast UBC13 homolog
  • ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)
  • ubiquitin-conjugating enzyme E2 N
  • UbcH-ben
  • bendless-like ubiquitin conjugating enzyme
  • UBC13
  • MGC131857
  • MGC8489
  • EC 6.3.2.19
  • ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)

Research Areas for UBE2N/Ubc13

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for UBE2N/Ubc13

Learn more about PTMs related to UBE2N/Ubc13.

Ubiquitination
Phosphorylation
Sumoylation
Cleavage
Reduction
Isgylation
Acetylation

Bioinformatics Tool for UBE2N/Ubc13

Discover related pathways, diseases and genes to UBE2N/Ubc13. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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