Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ca, Pm, Pm
Applications: WB, ICC/IF
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu, Mu, Rt
Applications: Enzyme Activity
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
9040 |
| Alternate Names |
- EC 6.3.2
- EC 6.3.2.-
- hUbc12
- NEDD8 carrier protein
- NEDD8 protein ligase
- UBC12NEDD8-conjugating enzyme Ubc12
- UBC-RS2
- ubiquitin carrier protein M
- Ubiquitin-conjugating enzyme E2 M
- ubiquitin-conjugating enzyme E2M (homologous to yeast UBC12)
- ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
- ubiquitin-protein ligase M
- yeast UBC12 homolog
|
