UBE2F/NCE2 Products

Antibodies
UBE2F/NCE2 Antibody
UBE2F/NCE2 Antibody
NBP1-92169
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UBE2F/NCE2 Antibody
UBE2F/NCE2 Antibody
NBP1-44062
Species: Hu, Mu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
UBE2F/NCE2 Antibody
UBE2F/NCE2 Antibody
NBP1-57602
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
UBE2F/NCE2 Overexpression Lys ...
UBE2F/NCE2 Overexpression Lysate (...
NBP2-05766
Applications: WB
Proteins
UBE2F/NCE2 Recombinant Protei ...
UBE2F/NCE2 Recombinant Protein Ant...
NBP1-92169PEP
Species: Hu
Applications: AC
UBE2F/NCE2 Recombinant Protei ...
UBE2F/NCE2 Recombinant Protein
NBP1-98922
Species: Hu
Applications: PAGE

Description

NCE2 is a ubiquitin conjugating enzyme. Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. The process of target selection, covalent attachment and shuttle to the 26S proteasome is a vital means of regulating the concentrations of key regulatory proteins in the cell by limiting their lifespans. Polyubiquitination is a common feature of this modification. Serial steps for modification include the activation of ubiquitin, an ATP dependent formation of a thioester bond between ubiquitin and the enzyme E1, transfer by transacylation of ubiquitin from E1 to the ubiquitin conjugating enzyme E2, and covalent linkage to the target protein directly by E2 or via E3 ligase enzyme. Deubiquitination enzymes also exist to reverse the marking of protein substrates. Posttranslational tagging by Ub is involved in a multitude of cellular processes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, stress responses, the immune response, and nervous system functions.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 140739
Alternate Names
  • EC 6.3.2
  • EC 6.3.2.-
  • NEDD8-conjugating enzyme UBE2F
  • NEDD8 conjugating enzyme
  • MGC18120
  • NEDD8-conjugating enzyme 2
  • NEDD8 protein ligase UBE2F
  • NEDD8 carrier protein UBE2F
  • NCE2Ubiquitin-conjugating enzyme E2 F
  • ubiquitin-conjugating enzyme E2F (putative)

Pathways for UBE2F/NCE2

View related products by pathway and learn more about each of the pathways below.

Conjugation

Bioinformatics Tool for UBE2F/NCE2

Discover related pathways, diseases and genes to UBE2F/NCE2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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