UAF1/WDR48 Products

Antibodies
UAF1/WDR48 Antibody
UAF1/WDR48 Antibody
NBP1-81404
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UAF1/WDR48 Antibody
UAF1/WDR48 Antibody
NBP2-49269
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Lysates
UAF1/WDR48 Overexpression Lys ...
UAF1/WDR48 Overexpression Lysate (...
NBP2-06599
Applications: WB
Proteins
UAF1/WDR48 Recombinant Protei ...
UAF1/WDR48 Recombinant Protein
H00057599-P01
Species: Hu
Applications: WB, ELISA, PA
UAF1/WDR48 Recombinant Protei ...
UAF1/WDR48 Recombinant Protein Ant...
NBP2-49269PEP
Species: Hu
Applications: AC
UAF1/WDR48 Recombinant Protei ...
UAF1/WDR48 Recombinant Protein Ant...
NBP1-81404PEP
Species: Hu
Applications: AC

Description

Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 by enhancing the USP1-mediateddeubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity ofcomplexes containing USP12 and USP46, respectively. Activates deubiquitination by increasing the catalytic turnoverwithout increasing the affinity of deubiquitinating enzymes for the substrate. In case of infection by Herpesvirussaimiri, may play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes.Induces lysosomal vesicle formation via interaction with Herpesvirus saimiri tyrosine kinase-interacting protein(TIP). Subsequently, TIP recruits tyrosine-protein kinase LCK, resulting in down-regulation of T-cell antigen receptorTCR. May play a role in generation of enlarged endosomal vesicles via interaction with TIP. In case of infection bypapillomavirus HPV11, promotes the maintenance of the viral genome via its interaction with HPV11 helicase E1

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 57599
Alternate Names
  • p80
  • USP1-associated factor 1
  • WD repeat-containing protein 48
  • UAF1
  • USP1 associated factor 1
  • P80
  • KIAA1449DKFZp686G1794
  • WD repeat endosomal protein
  • WD repeat domain 48

Diseases related to UAF1/WDR48

Discover more about diseases related to UAF1/WDR48.

Neoplasms
Papillomavirus Infections
Myeloproliferative Disease

Pathways for UAF1/WDR48

View related products by pathway and learn more about each of the pathways below.

Localization
Dna Replication
Histone Ubiquitination
Gastrulation
Gene Silencing
Cell Motility
Interferon-gamma Production
Endocytosis
Histone Deubiquitination

PTMs for UAF1/WDR48

Learn more about PTMs related to UAF1/WDR48.

Ubiquitination

Bioinformatics Tool for UAF1/WDR48

Discover related pathways, diseases and genes to UAF1/WDR48. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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