UACA Products

Antibodies
UACA Antibody
UACA Antibody
NB100-61622
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
UACA Antibody
UACA Antibody
NBP1-92554
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UACA Antibody (UACA/1222)
UACA Antibody (UACA/1222)
NBP2-44357
Species: Hu, Mu
Applications: WB, Flow, IF
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Lysates
UACA Overexpression Lysate (D ...
UACA Overexpression Lysate (Denatu...
H00055075-T01
Species: Hu
Applications: WB
Proteins
UACA Recombinant Protein Anti ...
UACA Recombinant Protein Antigen
NBP1-92554PEP
Species: Hu
Applications: AC
UACA Recombinant Protein Anti ...
UACA Recombinant Protein Antigen
NBP2-58742PEP
Species: Hu
Applications: AC

Description

UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats) was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 55075
Alternate Names
  • uveal autoantigen with coiled coil domains and ankyrin repeats
  • NUCLING
  • nuclear membrane binding protein
  • FLJ10128
  • KIAA1561MGC141969
  • MGC141967
  • uveal autoantigen with coiled-coil domains and ankyrin repeats

Research Areas for UACA

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for UACA

Learn more about PTMs related to UACA.

Cleavage
Methylation

Bioinformatics Tool for UACA

Discover related pathways, diseases and genes to UACA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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