UACA Products

Description

UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats) was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Bioinformatics

Entrez	55075 Human
Uniprot	NP_060473.2 Human Q9BZF9 Human
Product By Gene ID	55075
Alternate Names	FLJ10128 KIAA1561MGC141969 MGC141967 nuclear membrane binding protein NUCLING uveal autoantigen with coiled coil domains and ankyrin repeats uveal autoantigen with coiled-coil domains and ankyrin repeats

Research Areas for UACA

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Apoptosis