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Tumstatin/COL4A3 Products


Description

COL4A3 (Collagen, type IV, alpha 3) belongs to the type IV collagen family. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. Type IV collagen is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity.

Bioinformatics

Entrez
1285
Human
12828
Mouse
363265
Rat
Product By Gene ID 1285
Alternate Names
  • COL4A3
  • collagen alpha-3(IV) chain
  • collagen IV, alpha-3 polypeptide
  • collagen, type IV, alpha 3 (Goodpasture antigen)
  • Goodpasture antigen
  • Tumstatin

Research Areas for Tumstatin/COL4A3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Apoptosis
Cancer
Cardiovascular Biology
Cell Biology
Cytoskeleton Markers
Immunology
Signal Transduction