Tryptase beta-2/TPSB2 Products

Antibodies
Tryptase beta-2/TPSB2 Antibod ...
Tryptase beta-2/TPSB2 Antibody (34...
MAB37961
Species: Hu
Applications: WB, IP, Neut
Host: Mouse Monoclonal
Tryptase beta-2/TPSB2 Antibod ...
Tryptase beta-2/TPSB2 Antibody (34...
MAB3796
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Lysates
Tryptase beta-2/TPSB2 Overexp ...
Tryptase beta-2/TPSB2 Overexpressi...
NBL1-17230
Applications: WB
Proteins
Tryptase beta-2/TPSB2 Recombi ...
Tryptase beta-2/TPSB2 Recombinant ...
H00064499-P01
Species: Hu
Applications: WB, ELISA, PA

Description

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 64499
Alternate Names
  • tryptase beta II
  • EC 3.4.21
  • mast cell tryptase beta III
  • Tryptase-2
  • mast cell tryptase beta II
  • tryptaseC
  • tryptaseB
  • tryptase beta 2
  • tryptase-2
  • EC 3.4.21.59
  • tryptase III
  • Tryptase II
  • TPS2tryptase beta-2
  • tryptase beta III
  • tryptase beta 2 (gene/pseudogene)

PTMs for Tryptase beta-2/TPSB2

Learn more about PTMs related to Tryptase beta-2/TPSB2.

Cleavage

Bioinformatics Tool for Tryptase beta-2/TPSB2

Discover related pathways, diseases and genes to Tryptase beta-2/TPSB2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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