TRPV4 Products

Antibodies
TRPV4 Antibody
TRPV4 Antibody
NB110-74960
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TRPV4 Antibody
TRPV4 Antibody
NBP2-41262
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IF
Host: Rabbit Polyclonal
TRPV4 Antibody
TRPV4 Antibody
NBP1-20225
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Lysates
TRPV4 Overexpression Lysate ( ...
TRPV4 Overexpression Lysate (Native)
NBL1-17344
Species: Hu
Applications: WB
TRPV4 Overexpression Lysate ( ...
TRPV4 Overexpression Lysate (Native)
NBL1-17343
Species: Hu
Applications: WB

Description

TRPV4 is a cation-selective channel, activated in response to systemic osmotic pressure. FUNCTION: Non-selective calcium permanent cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. SUBUNIT: Interacts with calmodulin. Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed lung, spleen, kidney, testis, fat, and at very low levels in trigeminal ganglia. SIMILARITY: Belongs to the transient receptor family, TrpV subfamily. SIMILARITY: Contains 3 ANK repeats.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Mouse
Product By Gene ID 59341
Alternate Names
  • VRL2
  • Vanilloid receptor-related osmotically-activated channel
  • Vanilloid receptor-like channel 2
  • Vanilloid receptor-like protein 2
  • Transient receptor potential protein 12
  • TrpV4
  • Osm-9-like TRP channel 4
  • vanilloid receptor-related osmotically activated channel
  • VRL-2
  • transient receptor potential cation channel subfamily V member 4
  • VR-OAC
  • CMT2Cosmosensitive transient receptor potential channel 4
  • TRP12OSM9-like transient receptor potential channel 4
  • OTRPC4SSQTL1
  • VROACSPSMA
  • HMSN2C
  • transient receptor potential cation channel, subfamily V, member 4

Bioinformatics Tool for TRPV4

Discover related pathways, diseases and genes to TRPV4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

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