TRADD Products

Antibodies
TRADD Antibody
TRADD Antibody
NB100-56169
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
TRADD Antibody [Unconjugated] ...
TRADD Antibody [Unconjugated]
AF2658
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
TRADD Antibody (313203)
TRADD Antibody (313203)
MAB2658
Species: Hu
Applications: WB, ICFlow
Host: Mouse Monoclonal
Antibody Pairs
TRADD Antibody Pair
TRADD Antibody Pair
H00008717-PW1
Species: Hu
Applications: WB, IP
Lysates
TRADD Overexpression Lysate ( ...
TRADD Overexpression Lysate (Native)
NBL1-17238
Applications: WB
Proteins
TRADD Recombinant Protein
TRADD Recombinant Protein
H00008717-P01
Species: Hu
Applications: WB, ELISA, PA
TRADD Partial Recombinant Pro ...
TRADD Partial Recombinant Protein
H00008717-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
TRADD RNAi
TRADD RNAi
H00008717-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

TRADD [tumor necrosis factor receptor type 1-associated (TNFR1) death domain protein] is a death domain containing adaptor molecule that interacts with TNFR1/TNFRSF1A and mediates programmed cell death signaling and NF-kB activation (reviewed in Feng, 2005). TRADD binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thereby suppresses TRAF2 mediated apoptosis. TRADD can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. This antibody recognizes TRADD; human TRADD is a 312 amino acid protein.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 8717
Alternate Names
  • tumor necrosis factor receptor-1-associated protein
  • tumor necrosis factor receptor type 1-associated DEATH domain protein
  • tumor necrosis factor receptor type 1 associated death domain protein
  • MGC11078
  • TNFRSF1A-associated via death domainTNFR1-associated DEATH domain protein

Research Areas for TRADD

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Tumor Suppressors

Bioinformatics Tool for TRADD

Discover related pathways, diseases and genes to TRADD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TRADD Blog Posts

Check out the latest blog posts on TRADD.
Caspase 9: The Suicidal Cell Whisperer
Cell death via apoptosis is a key cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. Among the subclass of initiator caspases that include...    Read more.
Read more TRADD related blogs.