TPT1/TCTP Products

Antibodies
TPT1/TCTP Antibody (488411) [ ...
TPT1/TCTP Antibody (488411) [Uncon...
MAB4648
Species: Hu, Mu, Rt
Applications: WB, ICC
Host: Mouse Monoclonal
TPT1/TCTP Antibody (2C4)
TPT1/TCTP Antibody (2C4)
H00007178-M03
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
TPT1/TCTP Antibody
TPT1/TCTP Antibody
NB100-92315
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
TPT1/TCTP Overexpression Lysa ...
TPT1/TCTP Overexpression Lysate (N...
NBL1-17234
Applications: WB
Proteins
TPT1/TCTP Recombinant Protein ...
TPT1/TCTP Recombinant Protein
NBP1-37085
Species: Hu
Applications: PAGE
TPT1/TCTP Recombinant Protein ...
TPT1/TCTP Recombinant Protein Antigen
NBP2-38447PEP
Species: Hu
Applications: AC
TPT1/TCTP Recombinant Protein ...
TPT1/TCTP Recombinant Protein
NBP2-52093
Species: Mu
Applications: PAGE
RNAi
TPT1/TCTP RNAi
TPT1/TCTP RNAi
H00007178-R01
Species: Hu

Description

Histamine is an inflammatory mediator that is ubiquitously expressed and has a broad range of pharmacologic effects. Specifically, it plays a role in the central nervous, gastrointestinal, respiratory and immune systems. Histamine release is mediated by the stimulation of mast cells and basophils. Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family and is detected as a protein of 21 kDa in mice and 23 kDa in human. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down Syndrome.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7178
Alternate Names
  • Fortilin
  • p23
  • translationally-controlled tumor protein
  • Histamine-releasing factor
  • p02
  • TCTPHRFfortilin
  • FLJ27337
  • tumor protein, translationally-controlled 1

Research Areas for TPT1/TCTP

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for TPT1/TCTP

Learn more about PTMs related to TPT1/TCTP.

Phosphorylation
Dephosphorylation
Ribosylation

Bioinformatics Tool for TPT1/TCTP

Discover related pathways, diseases and genes to TPT1/TCTP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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