Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
WB, ELISA, ICC/IF, IHC-PHost:
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: RNAi, RNAi SP
TPMT encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Bioinformatics Tool for TPMT
Discover related pathways, diseases and genes to TPMT. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.