TPMT Products

Antibodies
TPMT Antibody (2A2)
TPMT Antibody (2A2)
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
TPMT Antibody (1B5)
TPMT Antibody (1B5)
H00007172-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
TPMT Antibody
TPMT Antibody
NBP1-86032
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
TPMT Overexpression Lysate (N ...
TPMT Overexpression Lysate (Native)
NBL1-17222
Applications: WB
Proteins
TPMT Recombinant Protein Anti ...
TPMT Recombinant Protein Antigen
NBP1-86032PEP
Species: Hu
Applications: AC
TPMT Recombinant Protein
TPMT Recombinant Protein
NBC1-18525
Species: Hu
Applications: PAGE
RNAi
TPMT RNAi
TPMT RNAi
H00007172-R01
Species: Hu

Description

TPMT encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7172
Alternate Names
  • Thiopurine methyltransferase
  • S-adenosyl-L-methionine:thiopurine S-methyltransferase
  • EC 2.1.1.67
  • thiopurine S-methyltransferase

PTMs for TPMT

Learn more about PTMs related to TPMT.

Methylation
Reduction
Phosphorylation
Cleavage
Acetylation
Oxidation

Bioinformatics Tool for TPMT

Discover related pathways, diseases and genes to TPMT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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