TLE1 Products

Description

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG

Bioinformatics

Entrez	7088 Human
Uniprot	NM_005077 Human NP_005068 Human NP_005068.2 Human Q04724 Human
Product By Gene ID	7088
Alternate Names	E(Sp1) homolog enhancer of split groucho 1 ESG ESG1Enhancer of split groucho-like protein 1 GRG1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) transducin-like enhancer of split 1, homolog of Drosophila E(sp1) transducin-like enhancer protein 1

Research Areas for TLE1

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Signal Transduction