THEM4 Products

Description

Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq]

Bioinformatics

Entrez	117145 Human
Uniprot	AAH65277.1 Human NP_444283 Human NP_444283.2 Human Q5T1C6 Human
Product By Gene ID	117145
Alternate Names	C-terminal modulator protein CTMPCarboxyl-terminal modulator protein MGC29636 thioesterase superfamily member 4