TeNT Light Chain/Tetanus Toxin Products

Antibodies
TeNT Light Chain/Tetanus Toxi ...
TeNT Light Chain/Tetanus Toxin Ant...
MAB6535
Species: Ct
Applications: WB, IP
Host: Mouse Monoclonal
TeNT Light Chain/Tetanus Toxi ...
TeNT Light Chain/Tetanus Toxin Ant...
NB100-63239
Species: Ba
Applications: WB, ELISA
Host: Goat Polyclonal
TeNT Light Chain/Tetanus Toxi ...
TeNT Light Chain/Tetanus Toxin Ant...
NBP1-05448
Species: Ba
Applications: WB, ELISA
Host: Mouse Monoclonal

Description

Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

Bioinformatics

Product By Gene ID 1061100
Alternate Names
  • Tetanus toxin light chain
  • Tetanus toxin heavy chain
  • Tetanus toxin chain L
  • Tetanus toxin chain H
  • Tentoxylysin

Bioinformatics Tool for TeNT Light Chain/Tetanus Toxin

Discover related pathways, diseases and genes to TeNT Light Chain/Tetanus Toxin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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