WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-readyHost:
Species: Rt, Pm-NHP
Applications: WB, Flow, Func, IHC-Fr, IHC-P, IP, ICC/IF
Host: Mouse Monoclonal
Applications: Flow, ICC/IF, IP
Host: Rabbit Monoclonal
The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.
|Product By Gene ID
- T-cell receptor, alpha (V
- T-cell antigen receptor, alpha polypeptide
- T cell receptor alpha locus
Pathways for TCR alpha/beta
View related products by pathway and learn more about each of the pathways below.PathogenesisLocalization
Bioinformatics Tool for TCR alpha/beta
Discover related pathways, diseases and genes to TCR alpha/beta. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.