TCF-3/E2A Products

Description

TCF3 / E2A encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

Bioinformatics

Entrez	171046 Rat 21423 Mouse 6929 Human
Uniprot	NM_003200 Human NP_003191 Human NP_003191.1 Human P15923 Human
Product By Gene ID	6929
Alternate Names	BHLHB21 bHLHb21TCF-3 Class B basic helix-loop-helix protein 21 E2A immunoglobulin enhancer-binding factor E12/E47 E2AKappa-E2-binding factor Immunoglobulin enhancer-binding factor E12/E47 Immunoglobulin transcription factor 1 ITF1Transcription factor ITF-1 MGC129647 MGC129648 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) Transcription factor 3 transcription factor E2-alpha VDIR VDR interacting repressor

Research Areas for TCF-3/E2A

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Transcription Factors and Regulators