TBX6 Products

Description

Tbx6 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures. Transcript variants encoding different isoforms have been noted for this gene.

Bioinformatics

Entrez	6911 Human
Uniprot	O95947 Human NP_004599 Human NP_004599.2 Human
Product By Gene ID	6911
Alternate Names	T-box transcription factor TBX6 DFNB67 T-box protein 6 T-box 6

Diseases related to TBX6

Discover more about diseases related to TBX6.

Congenital Abnormality
Autistic Disorder
Scoliosis, Unspecified
Dysequilibrium Syndrome
Crest Syndrome
Autism Spectrum Disorders
Melanoma
Learning Disabilities
Strabismus
Hernia, Inguinal
Vascular Anomaly
Malignant Neoplasms
Ulnar-mammary Syndrome Of Pallister
Chimera Disorder
Ectopic Tissue
Congenital Absence
Idiopathic Hypereosinophilic Syndrome
Atrophy
Blind Vision

Pathways for TBX6

View related products by pathway and learn more about each of the pathways below.

Segmentation
Gastrulation
Somitogenesis
Mesoderm Formation
Paraxial Mesoderm Formation
Mesoderm Development
Cell Differentiation
Muscle Cell Differentiation
Somite Specification
Localization
Cell Death
Neurogenesis
Intermediate Mesoderm Development
Cell Fate Specification
Paraxial Mesoderm Development
Reverse Transcription
Histone Acetylation
Eye Development
Neural Plate Development
Cell Proliferation

PTMs for TBX6

Learn more about PTMs related to TBX6.

Cleavage
Acetylation

Bioinformatics Tool for TBX6

Discover related pathways, diseases and genes to TBX6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.