TBC1D1 Products

TBC1D1 Antibody
TBC1D1 Antibody
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
TBC1D1 Antibody
TBC1D1 Antibody
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
TBC1D1 Antibody
TBC1D1 Antibody
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
TBC1D1 Overexpression Lysate
TBC1D1 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human TBC1D1 His ...
Recombinant Human TBC1D1 His Protein
Species: Hu
Applications: PAGE
TBC1D1 Recombinant Protein An ...
TBC1D1 Recombinant Protein Antigen
Species: Hu
Applications: AC


TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.


Entrez Human
Uniprot Human
Product By Gene ID 23216
Alternate Names
  • TBC1
  • TBC1 domain family member 1
  • KIAA1108TBC
  • TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1

PTMs for TBC1D1

Learn more about PTMs related to TBC1D1.


Bioinformatics Tool for TBC1D1

Discover related pathways, diseases and genes to TBC1D1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related TBC1D1 Blog Posts

Check out the latest blog posts on TBC1D1.
Muscle-specific UBE2O ablation requires activated AMPK alpha 2 to protect against metabolic syndrome
By Jamshed Arslan, Pharm. D., PhD. Generating energy (ATP) from nutrients is a recipe for life. One of the sensors of cellular energy levels is the serine/threonine kinase AMPK. This enzyme facilitates lipid oxidati...    Read more.
Read more TBC1D1 related blogs.