TBC1D1 Products

Antibodies
TBC1D1 Antibody
TBC1D1 Antibody
NBP1-54654
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
TBC1D1 Antibody
TBC1D1 Antibody
NB100-80834
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
TBC1D1 Antibody
TBC1D1 Antibody
H00023216-B02P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Antibody Pairs
TBC1D1 Antibody Pair
TBC1D1 Antibody Pair
H00023216-PW1
Species: Hu
Applications: WB, IP
Lysates
TBC1D1 Overexpression Lysate ...
TBC1D1 Overexpression Lysate (Native)
NBL1-16719
Applications: WB
TBC1D1 Overexpression Lysate ...
TBC1D1 Overexpression Lysate (Dena...
H00023216-T02
Applications: WB
Proteins
TBC1D1 Recombinant Protein An ...
TBC1D1 Recombinant Protein Antigen
NBP1-82928PEP
Species: Hu
Applications: AC
TBC1D1 Recombinant Protein
TBC1D1 Recombinant Protein
NBP2-22851
Species: Hu
Applications: PAGE
TBC1D1 Peptide
TBC1D1 Peptide
NBP1-76397PEP
Species: Hu
Applications: AC

Description

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2/USP6, yeast Bub2, and CDC16. TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles. TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity, and is a likely Akt substrate. Mutations in the Tbc1d1 gene lead to some cases of severe human obesity.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 23216
Alternate Names
  • TBC1
  • TBC1 domain family member 1
  • KIAA1108TBC
  • TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1

PTMs for TBC1D1

Learn more about PTMs related to TBC1D1.

Phosphorylation
Oxidation

Bioinformatics Tool for TBC1D1

Discover related pathways, diseases and genes to TBC1D1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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