Syntenin 1 Products

Description

Syntenin 1 is encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Bioinformatics

Entrez	53378 Mouse 6386 Human 83841 Rat
Uniprot	NP_001007068 Human NP_001007068.1 Human NP_005616 Human NP_005616.2 Human O00560 Human
Product By Gene ID	6386
Alternate Names	MDA9 MDA-9 melanoma differentiation associated protein-9 Melanoma differentiation-associated protein 9 Pro-TGF-alpha cytoplasmic domain-interacting protein 18 Scaffold protein Pbp1 ST1 SYCLTACIP18 syndecan binding protein (syntenin) Syndecan-binding protein 1 syntenin-1