Species: V-Vi
Applications: ICC/IF, IHC
Host: Mouse Monoclonal
Species: V-Vi
Applications: WB
Host: Rabbit Polyclonal
Species: V-Vi
Applications: ICC/IF, IHC
Host: Mouse Monoclonal
Description
SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
Bioinformatics
Alternate Names |
- Large T antigen
- Small T antigen
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