SUR-8 Products

Description

Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes

Bioinformatics

Entrez	8036 Human
Uniprot	NM_007373 Human NP_031399 Human AAH50445 Human
Product By Gene ID	8036
Alternate Names	SUR-8 Protein sur-8 homolog SOC-2 Protein soc-2 homolog SIAA0862 SOC2SUR8leucine-rich repeat protein SHOC-2 KIAA0862FLJ60412 soc-2 (suppressor of clear, C.elegans) homolog soc-2 suppressor of clear homolog (C. elegans)

Diseases related to SUR-8

Discover more about diseases related to SUR-8.

Noonan Syndrome
Dwarfism
Malignant Neoplasms
Neoplasms
Congenital Heart Defects
Hypertrophic Cardiomyopathy
Cardiomyopathies
Costello Syndrome (disorder)
Hypertrophy
Congenital Anomaly Of Face
Hematologic Neoplasms
Cardio-facio-cutaneous Syndrome
Leopard Syndrome
Developmental Disabilities
Cryptorchidism
Leukemia
Malnutrition
Loose Anagen Hair Syndrome

Pathways for SUR-8

View related products by pathway and learn more about each of the pathways below.

Anagen
Pathogenesis
Cell Proliferation
Programmed Cell Death
Regulation Of Signaling
Intracellular Signal Transduction
Endocytosis
Localization
Senescence
Lipid Modification
Cell Death
S Phase
Mapk Cascade
Autophagy

Research Areas for SUR-8

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for SUR-8

Learn more about PTMs related to SUR-8.

Phosphorylation
Myristoylation
Dephosphorylation

Bioinformatics Tool for SUR-8

Discover related pathways, diseases and genes to SUR-8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.