Stathmin 1 Products

Antibodies
Stathmin 1 Antibody (SS0453)
Stathmin 1 Antibody (SS0453)
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Monoclonal
Stathmin 1 Antibody
Stathmin 1 Antibody
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, KO
Host: Rabbit Polyclonal
Antibody Pairs
Stathmin 1 Antibody Pair
Stathmin 1 Antibody Pair
H00003925-PW1
Species: Hu
Applications: WB, IP
Lysates
Stathmin 1 Knockout HeLa Cell ...
Stathmin 1 Knockout HeLa Cell Lysate
NBP2-64648
Species: Hu
Applications: WB
Stathmin 1 Overexpression Lys ...
Stathmin 1 Overexpression Lysate
NBP2-10460
Species: Hu
Applications: WB
Stathmin 1 Overexpression Lys ...
Stathmin 1 Overexpression Lysate
NBP2-11309
Species: Hu
Applications: WB
Proteins
Recombinant Human Stathmin 1 ...
Recombinant Human Stathmin 1 Protein
NBC1-21276
Species: Hu
Applications: PAGE
Stathmin 1 Blocking Peptide
Stathmin 1 Blocking Peptide
NBP1-76798PEP
Species: Hu
Applications: AC

Description

Stathmin (oncoprotein 18, op18) is a ubiquitous cytosolic phosphoprotein with various regulatory functions in cell proliferation, differentiation signaling, and activation (1). In particular, stathmin is involved in the regulation of tubulin dynamics through inhibition of microtubule formation and/or microtubule depolymerization. Stathmin interacts with soulable tubulins (alpha,beta-tubulin) resulting in the formation of T2S complex which sequesters free tubulin, impeding tubulin formation (2). Stathmin activity is regulated through phosphorylation at Ser16, Ser25, Ser38 and Ser63 by various protein kinases (e.g. MAP-kinase, p34cdc2 kinase), weakening stathmin's affinity to tubulin (3). A mutation on stathmin can lead to excess build up of mitotic spindle and with possible consequence of unregulated cell cycles seen in cancer cells (4). Stathmin is also known as the generic member of a protein family which includes neural proteins SCG10, SCLIP and RB3/RB3/RB3. All members in this family exhibits tubulin binding ability.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 3925
Alternate Names
  • Protein Pr22
  • chromosome 1 open reading frame 215
  • pp19
  • C1orf215
  • pp17
  • Phosphoprotein p19
  • Prosolin
  • Oncoprotein 18
  • Op18
  • Leukemia-associated phosphoprotein p18
  • Metablastin
  • stathmin 1/oncoprotein 18
  • transmembrane protein C1orf215
  • PR22
  • stathmin
  • PP19
  • prosolin
  • PP17
  • phosphoprotein 19
  • Lag
  • metablastin
  • SMNLAP18FLJ32206
  • OP18MGC138870
  • MGC138869
  • stathmin 1

Research Areas for Stathmin 1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
CD Markers
Immunology
Microglia Markers
Neuroscience
Phospho-Specific
Signal Transduction

PTMs for Stathmin 1

Learn more about PTMs related to Stathmin 1.

Phosphorylation
Cleavage
Dephosphorylation
Methylation
Reduction
Deacetylation
Acetylation
Prenylation

Bioinformatics Tool for Stathmin 1

Discover related pathways, diseases and genes to Stathmin 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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