ST3GAL5 Products

Description

Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez	8869 Human
Uniprot	NP_003887
Product By Gene ID	8869
Alternate Names	3S-T alpha 2,3-sialyltransferase V CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase EC 2.4.99.9 Ganglioside GM3 Synthase GM3 synthase lactosylceramide alpha-2,3-sialyltransferase SATI sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase;GM3 synthase) Sialyltransferase 9 Siat9 SIATGM3S ST3 beta-galactoside alpha-2,3-sialyltransferase 5 ST3Gal V ST3GAL5 ST3GALV ST3GalVSIAT9SATI