Species: Hu
Applications: WB, Simple Western
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates
Bioinformatics
| Product By Gene ID |
10250 |
| Alternate Names |
- MGC39488
- POP101
- Ser/Arg-related nuclear matrix protein
- serine/arginine repetitive matrix 1
- serine/arginine repetitive matrix protein 1
- SRm160
- SRM160160-KD
- SR-related nuclear matrix protein of 160 kDa
|
