SRRM1 Products

Description

Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates

Bioinformatics

Entrez	10250 Human
Uniprot	NP_005830 Human NP_005830.2 Human
Product By Gene ID	10250
Alternate Names	MGC39488 POP101 Ser/Arg-related nuclear matrix protein serine/arginine repetitive matrix 1 serine/arginine repetitive matrix protein 1 SRm160 SRM160160-KD SR-related nuclear matrix protein of 160 kDa