SR-BI/SR-BII Products

SR-BI/SR-BII Antibody
SR-BI/SR-BII Antibody
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Polyclonal


High density lipoproteins (HDLs) play a critical role in cholesterol metabolism. This is evident in that their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.


Entrez Mouse
Product By Gene ID 949
Alternate Names
  • CD36 antigen
  • Collagen type I receptor, thrombospondin receptor-like 1
  • scavenger receptor class B type III
  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1
  • CD36L1scavenger receptor class B type 1
  • SRB1scavenger receptor class B member 1
  • SR-BIMGC138242
  • CLA1CD36 antigen-like 1
  • CD36 and LIMPII analogous 1
  • scavenger receptor class B, member 1

Research Areas for SR-BI/SR-BII

Find related products by research area and learn more about each of the different research areas below.

Cholesterol Metabolism
Lipid and Metabolism
Signal Transduction

Bioinformatics Tool for SR-BI/SR-BII

Discover related pathways, diseases and genes to SR-BI/SR-BII. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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