SPG21 Products

Antibodies
SPG21 Antibody
SPG21 Antibody
NBP1-89273
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SPG21 Antibody
SPG21 Antibody
NBP2-56164
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
SPG21 Antibody (2B11)
SPG21 Antibody (2B11)
H00051324-M01
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Lysates
SPG21 Overexpression Lysate ( ...
SPG21 Overexpression Lysate (Native)
NBL1-16395
Applications: WB
SPG21 Overexpression Lysate ( ...
SPG21 Overexpression Lysate (Native)
NBP2-09462
Applications: WB
Proteins
SPG21 Recombinant Protein Ant ...
SPG21 Recombinant Protein Antigen
NBP2-56164PEP
Species: Hu
Applications: B/N, Ctrl
SPG21 Recombinant Protein Ant ...
SPG21 Recombinant Protein Antigen
NBP1-89273PEP
Species: Hu
Applications: AC
Recombinant Human SPG21 Prote ...
Recombinant Human SPG21 Protein
NBC1-21650
Species: Hu
Applications: PAGE
Host: Human
RNAi
SPG21 RNAi
SPG21 RNAi
H00051324-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

SPG21 is encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 51324
Alternate Names
  • maspardin
  • Acid cluster protein 33
  • MASPARDIN
  • GL010
  • MASTBM-019
  • ACP33Spastic paraplegia 21 protein
  • Spastic paraplegia 21 autosomal recessive Mast syndrome protein
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome)

Pathways for SPG21

View related products by pathway and learn more about each of the pathways below.

Transport
Cell Activation
T Cell Activation
Cell Growth
Chromosome Organization
T Cell Costimulation
Pathogenesis
Protein Transport

Research Areas for SPG21

Find related products by research area and learn more about each of the different research areas below.

Neurodegeneration

Bioinformatics Tool for SPG21

Discover related pathways, diseases and genes to SPG21. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.